I don't see any reason why ioFTPD would care what the names are. If you were to delete user 0 and/or group 0 that will have impacts. The .ini file of course refers to the default user/group so that would have to be updated, and a number of scripts assume 0:0 as the defaults... I can't think of any specific case where the code itself uses 0:0 instead of the .ini values, but that doesn't mean it doesn't exist.
Change the name, but don't nuke the accounts and you'll be fine.
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